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Tetracycline
Tetracycline, Deschlorobiomycin, CAS # 60-54-8, is a broad-spectrum napthacene antibiotic that inhibits bacterial growth. | CAS: 60-54-8 | C22H24N2O8 | 444.44 g/mol
80.40€
Chemical Identifiers
| CAS | 60-54-8 |
|---|---|
| Molecular Formula | C22H24N2O8 |
| Molecular Weight (g/mol) | 444.44 |
| MDL Number | MFCD00151232 |
| InChI Key | JYHCQVWYCGHXGP-BPPSBWQWSA-N |
| PubChem CID | 54675776 |
| SMILES | CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O |
Description
Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages. It is a compound that has been shown to induce apoptosis in various cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Tetracycline is a semisynthetic compound derived from chlortetracycline, an isolate from Streptomyces aureofaciens
• Tetracycline is a broad-spectrum bacteriostatic that inhibits polypeptide formation by binding the 30S ribosomal subunit and preventing aminoacyl tRNA-mRNA complex formation
• It may have other bactericidal properties such as limited binding to the 50S subunit
Application
• Tetracycline has been shown to exhibit antiprotozoal properties
• It can be used to kill both gram-positive and gram-negative bacteria
• It is suitable for use in laboratory applications in resistance gene testing and research on infection
Chemical Identifiers
| 60-54-8 | |
| 444.44 | |
| JYHCQVWYCGHXGP-BPPSBWQWSA-N | |
| CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O |
| C22H24N2O8 | |
| MFCD00151232 | |
| 54675776 |
Specifications
| Tetracycline | |
| 60-54-8 | |
| Yellow | |
| MFCD00151232 | |
| 14,9196 | |
| JYHCQVWYCGHXGP-BPPSBWQWSA-N | |
| (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide | |
| 54675776 | |
| Tetracycline |
| Crystalline Powder | |
| 172°C to 174°C | |
| C22H24N2O8 | |
| 2230417 | |
| Limited solubility in water; Soluble in 1M HCl with heating. | |
| CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O | |
| 444.44 | |
| 444.43 |
Safety and Handling
GHS H Statement
H302
Harmful if swallowed.
P264b-P270-P301+P312-P330-P501c
H302
missing translation for 'einecsNumber' : 200-481-9
missing translation for 'rtecsNumber' : QI8750000
missing translation for 'tsca' : No
Recommended Storage : Keep cold
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Tetracycline
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
Hazard Statement
- H302-Harmful if swallowed.
Precautionary Statement
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
Supplemental information
- MIXTURE LIST-Contains : Tetracycline
RUO – Research Use Only
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